Manchester United will be determined to progress to the Europa League semi-finals when they face Lyon in the second leg of their quarter-final showdown at Old Trafford on Thursday night.
The tie is evenly poised at 2-2 following last week's first leg at the Groupama Stadium in France, meaning everything is still to play for in the quest to advance to the last-four of the competition.
Lyon grabbed a very late equaliser through Rayan Cherki after Joshua Zirkzee thought he had won the game for United with 88 minutes on the clock.
United followed that setback by losing 4-1 to Newcastle United in the Premier League at St James' Park on Sunday afternoon. Head coach Ruben Amorim rotated his pack for the trip north, making five changes amid the importance of the second tussle with Lyon.
Regarding the latest team news ahead of the clash with the Ligue 1 side, Amorim has confirmed Andre Onana will return in goal and replace Altay Bayindir after being taken out of the firing line at the weekend. Elsewhere, Matthijs de Ligt and Ayden Heaven will be unavailable, and Zirkzee is out for the rest of the season.
Ahead of being reinstated between the posts, Onana will be determined to atone for his two mistakes against Lyon last week and secure his first Europa League clean sheet since the 2-0 win over PAOK over November.
Amorim's decision to shuffle his pack against Newcastle offered an indication of what the starting XI might be against Lyon, meaning Harry Maguire is expected to be reinstated to the defence. He flanked Amorim at Wednesday's pre-match press conference and that was an indication he will start.
It is likely that he will start in the centre of the back-three, flanked by Noussair Mazraoui and Leny Yoro either side of him.
Harry Amass was given his full debut for United at the weekend, replacing Patrick Dorgu, but the Dane is highly likely to reclaim his place, meaning he should join Diogo Dalot in the wing-back positions.
Bruno Fernandes has recently made his way back to one of the two No.10 positions, meaning the prospect of that theme continuing against Lyon will likely see Casemiro reinstated to the team to start alongside Manuel Ugarte in the centre of midfield. Casemiro has started the last three matches in the Europa League.
The likelihood of those two joining forces in midfield means Fernandes will operate as one of the two No.10s. Alejandro Garnacho is likely to start alongside the Portuguese international after scoring and being substituted after just 55 minutes against Newcastle.
Rasmus Hojlund is the only available option to lead the line amid Zirkzee's injury blow. Chido Obi is unavailable for selection after being left out of United's revised squad ahead of the Europa League knockout stages commencing earlier this year.
United predicted line-up vs Lyon: Onana; Mazraoui, Maguire, Yoro; Dalot, Ugarte, Casemiro, Dorgu; Fernandes, Garnacho; Hojlund.
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